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Abstract:
I propose that in certain mental illnesses the mechanics for making, releasing, and responding to neurotransmitters are all normal; what is faulty is a portion of the mechanism whereby the brain recognizes abnormal behavior and feeds back on to the neuronal pathways producing the behavior to alter function of that neuronal system and re-establish normal behavior. All the above uses the physical structure of the brain. The existence of the feedback mechanism, and its perturbation, is deduced from data about the mechanism of antidepressants.