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Updated: Apr 17, 2026

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay
Published on: November 11, 2018
Protein lipid modifications and the regulation of ROP GTPase function
1Department of Molecular Biology and Ecology of Plants, Tel Aviv University, Tel Aviv 69978, Israel shauly@tauex.tau.ac.il.
Abstract:
In eukaryotes, the RHO superfamily of small G-proteins is implicated in the regulation of cell polarity and growth. Rho of Plants (ROPs)/RACs are plant-specific Rho family proteins that have been shown to regulate cell polarity, auxin transport and responses, ABA signalling, and response to pathogens. A hallmark of ROP/RAC function is their localization in specific plasma membrane domains. This short review focuses on the mechanisms responsible for membrane interactions of ROPs/RACs and how they affect ROP/RAC function.
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