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Related Concept Videos

Adult Stem Cells01:33

Adult Stem Cells

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Culturing Lymphocytes in Simulated Microgravity Using a Rotary Cell Culture System
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Behavior of stem cells under outer-space microgravity and ground-based microgravity simulation.

Cui Zhang1, Liang Li1, Jianling Chen1

  • 1Institute of Cell and Development Biology, College of Life Sciences, Zijingang Campus, Zhejiang University, Hangzhou, Zhejiang, 310058, P. R. China.

Cell Biology International
|February 26, 2015
PubMed
Summary
This summary is machine-generated.

Microgravity affects stem cell characteristics, including their shape, growth, movement, and specialization. This review summarizes key findings on how space conditions impact these crucial cells for regenerative medicine.

Keywords:
developmentdifferentiationmicrogravitystem cellstissue engineering

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Area of Science:

  • Space biology and regenerative medicine.

Background:

  • Space engineering advancements facilitate extensive life science research in space.
  • Stem cells are vital for regenerative medicine due to their differentiation potential.
  • Microgravity is a significant environmental factor studied in space medicine.

Purpose of the Study:

  • To review recent studies on the effects of microgravity on stem cells.
  • To elucidate the impact of space and simulated microgravity on stem cell properties.

Main Methods:

  • Literature review of studies investigating stem cells under microgravity.
  • Analysis of effects on stem cell morphology, proliferation, migration, and differentiation.

Main Results:

  • Microgravity influences stem cell morphology.
  • Stem cell proliferation and migration are affected by space conditions.
  • The differentiation potential of stem cells is altered in microgravity.

Conclusions:

  • Understanding microgravity's effects on stem cells is crucial for space medicine.
  • Stem cells show altered behavior under simulated and actual space conditions.
  • Further research is needed to fully harness stem cells in space environments.