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Essential elements in depression and anxiety. Part II.

Katarzyna Młyniec1, Magdalena Gaweł2, Urszula Doboszewska3

  • 1Department of Biochemical Toxicology, Jagiellonian University Medical College, Kraków, Poland.

Pharmacological Reports : PR
|February 26, 2015
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Summary

Essential elements like copper, selenium, manganese, iodine, and vanadium are linked to depression and anxiety. This review explores their dietary intake, serum levels, and roles as enzyme co-factors in neurobiology.

Keywords:
CopperDepressionIodineSeleniumTrace elements

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Area of Science:

  • Nutritional Neuroscience
  • Biochemistry
  • Psychiatry

Background:

  • Essential elements play crucial roles in biological processes.
  • Imbalances in nutrient levels are increasingly linked to mental health disorders.
  • Previous research has indicated potential connections between specific minerals and mood regulation.

Purpose of the Study:

  • To review the involvement of copper, selenium, manganese, iodine, and vanadium in depression and anxiety.
  • To explore the mechanisms linking these elements to the neurobiology of mood disorders.
  • To discuss the role of these elements as enzyme co-factors in the pathophysiology of depression and anxiety.

Main Methods:

  • Literature review of studies examining element levels and mood symptoms.
  • Analysis of research on the association between dietary intake/serum levels of elements and depression/anxiety.
  • Discussion of the role of essential elements as co-factors for enzymes implicated in mental health.

Main Results:

  • Specific essential elements (copper, selenium, manganese, iodine, vanadium) show associations with depression and anxiety symptoms.
  • Dietary intake and serum levels of these elements correlate with the prevalence or severity of mood disorders.
  • These elements function as vital co-factors for enzymes involved in neurotransmitter synthesis and neuronal function, impacting mental health.

Conclusions:

  • Essential elements are integral to the neurobiological underpinnings of depression and anxiety.
  • Further research into elemental balance and supplementation may offer novel therapeutic strategies for mood disorders.
  • Understanding the role of copper, selenium, manganese, iodine, and vanadium is crucial for addressing the complex etiology of depression and anxiety.