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Antibody-Free Assay for RNA Methyltransferase Activity Analysis
Published on: July 9, 2019
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A label-free electrochemical strategy for highly sensitive methyltransferase activity assays
Jiawan Zhou1, Xiaohua Zhang, Erhu Xiong
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P.R. China. chenjinhua@hnu.edu.cn.
Chemical Communications (Cambridge, England)
|February 26, 2015
Abstract:
A new electrochemical strategy for the simple and ultrasensitive evaluation of DNA methyltransferase (MTase) activity was developed based on electrocatalytic oxidation of ascorbic acid by graphene. In addition, the suitability of this sensing platform for MTase inhibitor screening was also demonstrated.
