Embryonal natural orifice transluminal endoscopic surgery treating severe acute pancreatitis complicated by abdominal...

This study aims to estimate the value of embryonal natural orifice transluminal endoscopic surgery (ENOTES) as a treatment for severe acute pancreatitis (SAP) complicated by abdominal compartment syndrome (ACS).

The patients who were randomized into ENOTES group and surgery group underwent ENOTES and laparotomy, respectively. The Efficacy and complications of these two treatments were compared.

Enterocinesia was observed earlier in patients of ENOTES group than that of surgery group. Acute Physiology and Chronic Health Evaluation II (APACHE II) score of patients in ENOTES group was superior to that of surgery group on the 1st, 3rd and 5th day after treatment (P < 0.05). The cure rate was 96.87% in ENOTES group, which was statistically different from 78.12% in surgery group (P < 0.05). Significant differences in complications and mortality were observed between two groups (P < 0.01).

Compared with surgical abdominal decompression, ENOTES and flexible endoscope therapy is a more effective and minimal invasive surgery with less complications.