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Risk factors associated with respiratory disorders in late preterm infants

Sachie Suga1, Ichiro Yasuhi1, Mikihiro Aoki1

  • 1a Department of Obstetrics and Gynecology , Perinatal Center, NHO Nagasaki Medical Center , Omura City , Japan .

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|February 26, 2015
PubMed

Insights

Respiratory problems are common in late preterm infants. Earlier gestational age, cesarean birth, and low Apgar scores are key risk factors for neonatal respiratory disorders.

Area of Science:

  • Neonatal Medicine
  • Perinatology
  • Pediatric Respiratory Health

Background:

  • Late preterm infants (34–36 weeks gestation) face significant risks for respiratory complications.
  • Identifying specific risk factors is crucial for timely intervention and improved outcomes.

Purpose of the Study:

  • To identify independent risk factors for neonatal respiratory disorders (NRD) in Japanese late preterm infants.
  • To inform clinical management strategies for this vulnerable population.

Main Methods:

  • Retrospective multicenter study of singleton late preterm deliveries (34–36 weeks gestation).
  • Exclusion of infants with congenital anomalies.
  • Definition of NRD included mechanical ventilation or nasal CPAP.
  • Analysis of perinatal risk factors.

Main Results:

  • A total of 683 infants were included.
  • NRD incidence was 13.7% at 34 weeks, 6.8% at 35 weeks, and 2.6% at 36 weeks.
  • Independent risk factors for NRD were earlier gestational age, cesarean birth, and low Apgar score.

Conclusions:

  • Earlier gestational age, cesarean delivery, and low Apgar scores are significant independent risk factors for NRD in late preterm infants.
  • Infants with these risk factors require management in an intensive delivery setting.
Abstract

Keywords:
Cesarean sectionlate preterm birthneonatal respiratory disorder

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