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Published on: March 27, 2018
Key articles and guidelines in the management of patients undergoing cardiac surgery
Ian B Hollis1, Douglas L Jennings2, Carrie S Oliphant3
1Department of Pharmacy, University of North Carolina Hospitals, Chapel Hill, NC, USA UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA ihollis@unch.unc.edu.
Insights
This guide details medication management for cardiac surgery patients, covering arrhythmias, infections, and bleeding risks. It focuses on optimizing outcomes with pharmacotherapy for coronary artery bypass grafting and mechanical circulatory support.
Area of Science:
- Cardiology
- Pharmacology
- Critical Care Medicine
Background:
- Cardiac surgery is frequently performed worldwide.
- Established evidence exists for medication management in coronary artery bypass grafting (CABG), valve surgery, and mechanical circulatory support (MCS).
Purpose of the Study:
- To provide the first compilation of guidelines and key articles on perioperative medication management for cardiac surgery patients.
- To focus on pharmacotherapy for optimizing patient outcomes.
Main Methods:
- Review of existing evidence and guidelines.
- Compilation of key articles relevant to cardiac surgery medication management.
Main Results:
- Guidelines address perioperative arrhythmias, antimicrobial prophylaxis, and thrombosis/bleeding management.
- Focus on antiplatelet and anticoagulant therapy optimization.
- Pharmacotherapy strategies for short- and long-term outcomes are discussed.
Conclusions:
- This compilation offers comprehensive guidance on medication management for cardiac surgery.
- Optimizing pharmacotherapy is crucial for improving patient outcomes after cardiac procedures.
Abstract:
Significant numbers of patients undergo cardiac surgery worldwide each year. A large evidence base exists regarding the optimal pre-, intra-, and postoperative mediation management for patients undergoing coronary artery bypass grafting (CABG) surgery, valve replacements or repairs, and mechanical circulatory support (MCS). Prevention and treatment of perioperative arrhythmias, perioperative antimicrobial prophylaxis, prevention of thrombosis, and bleeding through proper management of perioperative antiplatelet and anticoagulant therapies, and the use of pharmacotherapy to optimize both short- and long-term patient outcomes after cardiac surgery are the focus of this first compilation of guidelines and key articles in this patient population to be published in the Journal of Pharmacy Practice.
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