Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Feedback Inhibition00:46

Feedback Inhibition

59.0K
Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
59.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Motor automaticity in natural keyboard typing.

bioRxiv : the preprint server for biology·2026
Same author

A systematic investigation reveals dissociable effects of ageing on implicit and explicit components of sensorimotor learning.

Nature human behaviour·2026
Same author

Risk factors for extended hospital stay after anterior cervical discectomy and fusion: A national versus institutional comparison using propensity score matching.

Journal of craniovertebral junction & spine·2026
Same author

Cerebellar contributions to action and cognition: Prediction, timescale, and continuity.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Vascular Steal in White Matter of Non-Flow-Limited Cerebral Hemispheres Following Acetazolamide Challenge Using Arterial Spin Labeling Magnetic Resonance Imaging.

Brain sciences·2026
Same author

Motor biases reflect a misalignment between visual and proprioceptive reference frames.

eLife·2026

Related Experiment Video

Updated: Apr 16, 2026

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
08:55

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition

Published on: February 8, 2018

9.9K

Inhibition during response preparation is sensitive to response complexity.

Ian Greenhouse1, Dylan Saks2, Timothy Hoang2

  • 1Department of Psychology, University of California, Berkeley, California igreenhouse@berkeley.edu.

Journal of Neurophysiology
|February 27, 2015
PubMed
Summary

Movement preparation involves suppressing motor system excitability. Increased preparatory inhibition aids response selection for complex, simultaneous movements, but not sequential ones.

Keywords:
TMSinhibitionmotor controlresponse complexityresponse preparation

More Related Videos

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
09:43

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

Published on: August 10, 2014

47.3K
A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

6.5K

Related Experiment Videos

Last Updated: Apr 16, 2026

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
08:55

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition

Published on: February 8, 2018

9.9K
The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents
09:43

The 5-Choice Serial Reaction Time Task: A Task of Attention and Impulse Control for Rodents

Published on: August 10, 2014

47.3K
A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance
07:19

A Modified Lean and Release Technique to Emphasize Response Inhibition and Action Selection in Reactive Balance

Published on: March 19, 2020

6.5K

Area of Science:

  • Neuroscience
  • Motor Control
  • Cognitive Neuroscience

Background:

  • Motor system excitability is transiently suppressed during movement preparation.
  • This preparatory inhibition is thought to facilitate response selection and initiation.
  • Movement complexity may influence preparatory inhibition due to increased demands on selection and initiation.

Purpose of the Study:

  • To investigate the influence of movement complexity on preparatory inhibition.
  • To determine if preparatory inhibition aids response selection by suppressing extraneous movements.

Main Methods:

  • Probed corticospinal excitability using single-pulse transcranial magnetic stimulation during a delayed-response task.
  • Measured motor evoked potentials (MEPs) from the first dorsal interosseous (FDI) muscle.
  • Varied movement complexity involving single or multiple muscle coordination (simultaneous or sequential).

Main Results:

  • MEP suppression was greater for complex responses requiring simultaneous coordination of FDI and adductor digiti minimi compared to simpler FDI-only responses.
  • This increased inhibition was absent for complex responses involving sequential muscle movements.
  • Movement complexity did not affect inhibition levels when the response hand was fixed.

Conclusions:

  • Preparatory inhibition contributes to response selection, particularly for simultaneous multi-effector coordination.
  • Inhibition may suppress extraneous movements during complex response preparation.
  • The role of preparatory inhibition in movement control is dependent on response characteristics like complexity and effector coordination.