Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Early Endosome: Endocytosis of Transferrin

The Early Endosome: Endocytosis of Transferrin

Essential proteins such as insulin or low-density lipoprotein (LDL) and micronutrients such as iron enter a eukaryotic cell through receptor-mediated endocytosis. Subsequently, the early endosomes fuse with the vesicles containing such receptor-ligand complexes and play a vital role in sorting the incoming ligands and receptors. While the ligands are either degraded inside the vesicle or released into the cytosol, their receptors are returned to the plasma membrane for further rounds of...

EDTA: Auxiliary Complexing Reagents

EDTA: Auxiliary Complexing Reagents

EDTA titrations are usually carried out in highly basic conditions, where the fully deprotonated form of EDTA, Y4−, actively complexes with the free metal ions in the solution. Several metal ions precipitate as hydrous oxide (hydroxides, oxides, or oxyhydroxides) under these conditions, lowering the concentration of free metal ions in the solution. For this reason, auxiliary complexing agents or ligands such as ammonia, tartrate, citrate, or triethanolamine are used in EDTA titrations to...

Microbes and Other Elemental Cycles

Microbes and Other Elemental Cycles

Microbial activity plays a pivotal role in the biogeochemical cycling of iron and manganese, especially at the redox gradients characteristic of stratified aquatic environments. These cycles are driven by microbial transformations between oxidized and reduced forms of the metals, allowing organisms to exploit them for metabolic energy and structural purposes.Iron Cycling Across Redox GradientsIn neutral, oxygen-rich surface waters, iron is predominantly found in its oxidized, insoluble ferric...

Extraction: Advanced Methods

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prospective Audit and Feedback of Targeted Antimicrobials Use at a Tertiary Care Hospital in the United Arab Emirates.

Antibiotics (Basel, Switzerland)·2025

Same author

Sulopenem Etzadroxil/Probenecid.

Hospital pharmacy·2025

Same author

Axatilimab.

Hospital pharmacy·2025

Same author

Respiratory Syncytial Virus Vaccine (mRNA).

Hospital pharmacy·2024

Same author

Resmetirom.

Hospital pharmacy·2024

Same author

Cefepime/Enmetazobactam.

Hospital pharmacy·2024

Search research articles

Related Experiment Video

Updated: Apr 16, 2026

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

Ferric citrate.

Dennis J Cada¹, Jasen Cong², Danial E Baker³

¹Founder and Contributing Editor, The Formulary , Washington State University , Spokane, Washington.

Hospital Pharmacy

|February 27, 2015

Summary

The Formulary Monograph Service provides monthly drug monographs and utilization evaluations for Pharmacy & Therapeutics Committees. This service aids in informed drug selection and safe medication use for healthcare facilities.

More Related Videos

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

Published on: June 29, 2015

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Published on: February 23, 2024

Related Experiment Videos

Last Updated: Apr 16, 2026

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel

Published on: June 29, 2015

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Author Spotlight: Assessing the Impact of Novel Iron Chelators on Cancer Cell Metabolism

Published on: February 23, 2024

Area of Science:

Pharmacology
Drug Information
Healthcare Management

Background:

The Formulary Monograph Service offers detailed drug information crucial for clinical decision-making.
Pharmacy & Therapeutics Committees require timely data on new and emerging pharmaceutical agents.

Purpose of the Study:

To provide subscribers with comprehensive monographs on newly released and late-stage trial drugs.
To deliver monthly drug utilization evaluations (DUE/MUE) for optimizing medication use.
To support pharmacy and nursing staff with concise summaries and drug class reviews.

Main Methods:

Publication of 5-6 detailed monographs per month covering new and investigational drugs.
Inclusion of a 1-page summary monograph for quick reference and in-service use.
Provision of a comprehensive drug utilization evaluation/medication use evaluation (DUE/MUE) monthly.

Main Results:

Subscribers receive print and online access to monographs, including customized options.
A monthly drug class review is now integrated into the service.
February 2015 topics included netupitant/palonosetron, naltrexone SR/bupropion SR, nintedanib, pirfenidone, and ivabradine, with a safety MUE on netupitant/palonosetron.

Conclusions:

The Formulary Monograph Service is a valuable resource for healthcare facilities seeking evidence-based drug information.
The service supports informed formulary management and safe medication practices.
Continuous updates and evaluations facilitate optimal drug therapy selection and utilization.