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Novel Hormone Receptors Present in Apocrine Cystadenoma of the Eyelid
Sarah E Brown1, Alan H Friedman, Robert G Phelps
1*Department of Ophthalmology; and †Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, U.S.A.
Abstract:
A 53-year-old woman presented with an apocrine cystadenoma of the right upper eyelid. Histologic examination revealed proliferating epithelial cells with apocrine snouts and occasional mitotic figures. Immunohistochemical analysis revealed a Ki-67 index of 15% and positive staining for synaptophysin, chromogranin, estrogen receptor, progesterone receptor, gross cystic disease fluid protein (GCDFP)-15, and mammoglobin. The complement of positive immunomarkers in this case reinforces the importance of total excision and careful histologic assessment.
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