Related Experiment Video
Updated: Apr 16, 2026

An Ex Vivo Tissue Culture Model for Fibrovascular Complications in Proliferative Diabetic Retinopathy
Published on: January 25, 2019
Chronic myeloid leukemia diagnosed in a patient with uncontrolled proliferative diabetic retinopathy
Lígia M Figueiredo1, Renata T Rothwell, Dália Meira
1Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia, Vila Nova de Gaia, Portugal.
Purpose:
To report a case of uncontrolled proliferative diabetic retinopathy as an initial manifestation of chronic myeloid leukemia.
Methods:
Case report.
Patients:
A 55-year-old man with moderate nonproliferative diabetic retinopathy who rapidly developed proliferative retinopathy and bilateral neovascular glaucoma despite good glycemic control.
Conclusion:
Other pathologies should be excluded in diabetic patients with a rapid and severe progression in their retinopathy despite adequate metabolic control. These patients should be treated promptly and aggressively until systemic disease is stable.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

