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Colorectal cancer screening and surveillance in the elderly: updates and controversies
Lukejohn W Day1, Fernando Velayos2
1Division of Gastroenterology, Department of Medicine, San Francisco General Hospital and Trauma Center CA, USA.
Abstract:
Colorectal cancer is common worldwide, and the elderly are disproportionately affected. Increasing age is a risk factor for the development of precancerous adenomas and colorectal cancer, thus raising the issue of screening and surveillance in older patients. Elderly patients are a diverse and heteroge-neous group, and special considerations such as comorbid medical conditions, functional status and cognitive ability play a role in deciding on the utility of screening and sur-veillance. Colorectal cancer screening can be beneficial to patients, but at certain ages and under some circumstances the harm of screening outweighs the benefits. Increasing ad-verse events, poorer bowel preparation and more incomplete examinations are observed in older patients undergoing colo-noscopy for diagnostic, screening and surveillance purposes. Decisions regarding screening, surveillance and treatment for colorectal cancer require a multidisciplinary approach that accounts not only for the patient's age but also for their overall health, preferences and functional status. This review provides an update and examines the challenges surround-ing colorectal cancer diagnosis, screening, and treatment in the elderly.
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