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A highly porous medical metal-organic framework constructed from bioactive curcumin
Hongmin Su1, Fuxing Sun, Jiangtao Jia
1State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130021, P. R. China. zhugs@jlu.edu.cn.
Chemical Communications (Cambridge, England)
|February 28, 2015
Abstract:
A highly porous bio-MOF, medi-MOF-1, constructed from Zn and the pharmaceutical ingredient curcumin has been successfully synthesized. It can display permanent porosity with a surface area as high as ca. 3002 m(2) g(-1), which exhibits great potential in bioapplications. Its ibuprofen delivery ability, biodegradation and cytotoxicity were also studied.
