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Delivering nanomedicines to patients: a practical guide
Mike A W Eaton1, Laurent Levy2, Olivier M A Fontaine1
1European Technology Platform on Nanomedicine - ETPN, ETPN Secretariat c/o VDI-VDE Innovation+Technik GmbH, Berlin, Germany.
Nanomedicine : Nanotechnology, Biology, and Medicine
|March 1, 2015
Summary
Researchers need to understand industrial decision points to improve nanomedicine success rates. This perspective guides researchers and small and medium-sized enterprises (SMEs) through the drug development process from ideation to first-in-man trials.
Area of Science:
- Nanomedicine development in Europe.
- Translational research in drug development.
Background:
- The nanomedicine field has advanced significantly over the last decade.
- The ultimate goal is to translate nanomedicine concepts into clinical products.
Purpose of the Study:
- To provide a perspective on the current state of nanomedicine development in Europe.
- To guide researchers and SMEs in understanding industrial decision points for drug development.
- To map the early stages of nanomedicine development from ideation to first-in-man (FIM) trials.
Main Methods:
- This article presents a perspective based on the current state of nanomedicine development.
- It outlines key industrial decision points crucial for successful drug translation.
- It maps the early stages of the development process.
Main Results:
- A higher translational success rate for nanomedicines is achievable.
- Understanding industrial requirements early in development is critical for success.
- Researchers and SMEs can better navigate the development pathway.
Conclusions:
- Integrating industrial considerations early enhances the likelihood of nanomedicine success.
- Clearer understanding of the development process benefits all stakeholders.
- This perspective aims to aid researchers and SMEs in strategic development planning.
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