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Imaging in drug development.

James Nairne1, Peter B Iveson1, Andreas Meijer2

  • 1GE Healthcare, The Grove Centre, Amersham, Buckinghamshire, United Kingdom.

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Summary
This summary is machine-generated.

Advanced imaging techniques like magnetic resonance imaging (MRI) and functional MRI (fMRI), alongside nuclear medicine, are revolutionizing pharmaceutical development by providing deeper insights into disease mechanisms.

Keywords:
Clinical trialsFluorine-18ImagingMRIPETRadiochemistrySPECT

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Area of Science:

  • Medical imaging
  • Pharmaceutical development
  • Radiochemistry

Background:

  • Imaging is crucial for disease diagnosis and understanding mechanisms.
  • It is now set to significantly influence pharmaceutical development.
  • Technological advancements are key to this evolution.

Purpose of the Study:

  • To discuss the technologies enabling imaging's role in pharmaceutical development.
  • To outline the potential of magnetic resonance imaging (MRI) and functional MRI (fMRI).
  • To highlight advancements in nuclear medicine and radiotracer synthesis.

Main Methods:

  • Review of current imaging technologies.
  • Exploration of magnetic resonance imaging (MRI) and functional MRI (fMRI) potentials.
  • Discussion of new methods for enhanced scan information.
  • Overview of nuclear medicine advancements and radiotracer development.

Main Results:

  • Imaging technologies are advancing rapidly.
  • New methods provide richer data from MRI and fMRI scans.
  • Nuclear medicine is experiencing increased interest due to new radiotracers.

Conclusions:

  • Imaging technologies are well-positioned to impact pharmaceutical development.
  • MRI, fMRI, and nuclear medicine offer significant potential.
  • Continued innovation in radiochemistry will drive further progress.