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Caffeine and headache: specific remarks.

C A Espinosa Jovel1, F E Sobrino Mejía1

  • 1Neurología, Facultad de Medicina, Universidad de la Sabana, Bogotá, Colombia; Departamento de Neurología, Hospital Occidente de Kennedy, Bogotá, Colombia.

Neurologia (Barcelona, Spain)
|March 3, 2015
PubMed
Summary
This summary is machine-generated.

Excessive caffeine intake can cause various health issues, including headaches. This review examines caffeine

Keywords:
AdenosinaAdenosineAdultosAdultsAnalgesicsAnalgésicosCafeínaCaffeineCefalea crónica diariaDaily chronic headacheMigraineMigraña

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Area of Science:

  • Neuroscience
  • Pharmacology
  • Physiology

Background:

  • Caffeine is the world's most consumed psychostimulant.
  • Excessive intake leads to acute and chronic physiological changes.
  • These changes can manifest as cognitive decline, depression, fatigue, insomnia, cardiovascular issues, and headaches.

Purpose of the Study:

  • To analyze the physiological mechanisms of caffeine.
  • To explore the relationship between caffeine consumption and headache.

Main Methods:

  • Literature review of physiological mechanisms.
  • Analysis of studies on caffeine's effects on the nervous system.
  • Examination of caffeine's role in headache pathophysiology.

Main Results:

  • Chronic caffeine use can induce cortical hyperexcitability.
  • This hyperexcitability contributes to a pro-nociceptive state.
  • Caffeine can intensify primary headaches or trigger analgesic overuse headaches.

Conclusions:

  • Caffeine's physiological effects are complex and widespread.
  • Understanding these mechanisms is crucial for managing caffeine-related health issues.
  • Caffeine's role in headache requires careful consideration, especially regarding overuse.