Related Experiment Video For Cancer de la cavité buccale
Updated: Apr 16, 2026

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
Published on: April 3, 2026
[Feasability study of screening for malignant lesions in the oral cavity targeting tobacco users]
S Dakpé1, C Neiva1, S Testelin1
1Service de chirurgie maxillofaciale et stomatologie, CHU d'Amiens, place Victor-Pauchet, 80000 Amiens, France; Institut Faire Faces, CHU d'Amiens, place Victor-Pauchet, 80000 Amiens, France.
Introduction:
Oral cavity cancer is frequent. Prognosis of this cancer is closely linked to the development. Although the oral cavity is a potentially accessible site for examination, up to 50% of oral cancers are not detected until the disease is well advanced.
Patients And Method:
In a region where incidence rate is particularly high, local teams involved in screening, in epidemiological survey, in diagnosis and treatment of oral cancer performed a pilot feasibility study to improve strategy of early detection of oral cancer and premalignant lesion. Tobacco venders were solicited to distribute a flyer, which invite smokers to a free examination by general practitioner. General practitioners were invited to examine smokers, and to fill a predeterminate systematic oral cavity examination record during 3 months. They were asked to refer to a specialist if there was a potentially malignant disorder.
Results:
The involvement of tobacco venders was rated as 67.3%. Ninety-three patients were included in 3 months. General practitioners referred 27% of the examinated patients. Among them, only 63.6% really saw a specialist, and a premalignant lesion was confirmed in 15.3%; further exams were carried out in 28.6%; a benign lesion was diagnosed in 57.1%.
Discussion/Conclusion:
Original incentives for oral cavity screening were performed, based on multidisciplinary network. Nevertheless, it remains hardship to reach the targeted population and to maintain the patients in health system.

