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Updated: Apr 16, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer

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Published on: February 3, 2023

Primary thyroid lymphoma: multi-slice computed tomography findings.

Xu-Bin Li¹, Zhao-Xiang Ye

¹Department of Radiology, Tianjin Medical University Cancer Institute and Hospital; National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin, Huan-hu-xi Road, Hexi District, Tianjin, China

Asian Pacific Journal of Cancer Prevention : APJCP

|March 5, 2015

Summary

This summary is machine-generated.

Primary thyroid lymphoma (PTL) is rare, often seen in older patients with Hashimoto's thyroiditis. Multidetector-row computed tomography (MSCT) reveals characteristic features, aiding diagnosis and distinguishing it from other thyroid masses.

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Area of Science:

Radiology
Oncology
Pathology

Background:

Primary thyroid lymphoma (PTL) is an uncommon malignancy.
Increased awareness of PTL's imaging characteristics is crucial for accurate diagnosis.

Purpose of the Study:

To investigate the multidetector-row computed tomography (MSCT) features of PTL.
To improve diagnostic recognition of PTL among clinicians and radiologists.

Main Methods:

Retrospective review of clinicopathological data and MSCT images from 27 PTL patients.
Classification of MSCT appearances into three distinct patterns based on lesion morphology and distribution.

Main Results:

The study included patients with a mean age of 68, many with Hashimoto's thyroiditis and cervical lymphadenopathy.
The most common histological subtype was diffuse large B-cell lymphoma (DLBCL).
MSCT findings included masses affecting multiple thyroid lobes, ill-defined margins, homogeneous attenuation, and post-contrast enhancement. Type 3 (diffusely enlarged gland) was most frequent.

Conclusions:

PTL should be considered in elderly patients with Hashimoto's thyroiditis and cervical lymphadenopathy.
Key MSCT characteristics include diffuse involvement, isointensity to muscle, and enhancement. DLBCL subtype shows higher invasiveness.