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Outcomes of basal cell carcinomas directly invading the parotid gland
Kevin N Christensen1, Gregory P Henderson, Thomas L Hocker
1*Department of Dermatology, Mayo Clinic, Rochester, Minnesota; †Department of Dematology, Kaiser Permanente, Los Angeles, California.
Background:
Parotid involvement by basal cell carcinoma (BCC) is rare, and therefore management is controversial.
Objective:
To review the treatment and outcomes of patients with BCC involving the parotid by direct infiltration.
Methods And Materials:
The authors performed a retrospective chart review of BCC cases involving the parotid.
Results:
From 1994 to 2007, there were 19 cases of BCC involving the parotid gland by direct extension. Nine were primary tumors, and 10 recurrent (nonprimary). Eight tumors were treated with Mohs micrographic surgery (MMS), and 11 with wide local excision (WLE). One patient died of unrelated causes 5 months after treatment, and 2 did not follow up. The remaining 16 cases had an average follow-up of 55.2 months (range, 18-112 months). No primary BCC recurred after treatment. Six of 10 nonprimary BCC (60%) recurred, 2 of 10 metastasized, and 1 of 10 died of metastatic BCC. Two recurrences occurred after MMS, and 4 occurred after WLE with or without parotidectomy.
Conclusion:
Mohs micrographic surgery or WLE with intra-operative margin control seems to be an acceptable first-line treatment for primary BCC involving the parotid. Recurrent BCC involving the parotid gland through direct infiltration has high rates of future recurrence, and adjuvant treatment may be required.
