Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Catalysis02:50

Catalysis

32.6K
The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
32.6K
The Looking Glass Self01:28

The Looking Glass Self

605
The concept of the looking-glass self describes how an individual's self-concept is shaped by their perception of how others see them. This psychological theory, first introduced by sociologist Charles Horton Cooley in 1902, posits that self-identity emerges in a social context and is influenced by the judgments—real or imagined—of others.Research suggests that individuals frequently overestimate how positively others perceive them. This is particularly evident in physical...
605
Catalytically Perfect Enzymes01:07

Catalytically Perfect Enzymes

5.5K
The theory of catalytically perfect enzymes was first proposed by W.J. Albery and J. R. Knowles in 1976. These enzymes catalyze biochemical reactions at high-speed. Their catalytic efficiency values range from 108-109 M-1s-1. These enzymes are also called 'diffusion-controlled' as the only rate-limiting step in the catalysis is that of the substrate diffusion into the active site. Examples include triose phosphate isomerase, fumarase, and superoxide dismutase.
 
Most enzymes...
5.5K
Nonconscious Mimicry01:13

Nonconscious Mimicry

5.2K
Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.
5.2K
Heterogeneous Catalysis01:22

Heterogeneous Catalysis

129
Heterogeneous catalysis involves a catalyst in a different phase from the reactants. It is a process where the catalyst and the reactants are in distinct phases, typically solid and gas or liquid.Most heterogeneous catalysts are metals, metal oxides, or acids. The list includes transition metals like iron (Fe), cobalt (Co), nickel (Ni), palladium (Pd), platinum (Pt), chromium (Cr), manganese (Mn), tungsten (W), silver (Ag), and copper (Cu). These metals possess partially vacant d orbitals that...
129
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

56.9K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

LiraSearch-ultrafast ligand shape and electrostatic matching server.

Bioinformatics advances·2026
Same author

Are we there yet with XNA aptamers?

RSC advances·2026
Same author

Beyond CEN.PK - parallel engineering of selected S. cerevisiae strains reveals that superior chassis strains require different engineering approaches for limonene production.

Metabolic engineering·2025
Same author

Navigating directed evolution efficiently: optimizing selection conditions and selection output analysis.

Frontiers in molecular biosciences·2024
Same author

From competition to cure: the development of live biotherapeutic products for anticancer therapy in the iGEM competition.

Frontiers in bioengineering and biotechnology·2024
Same author

Melodia: A Python Library for Protein Structure Analysis.

Bioinformatics (Oxford, England)·2024
Same journal

Sustainable Synthesis of Bio-Based Furanic and Aromatic Amines Using an Optimized Whole-Cell Transaminase-Decarboxylase Cascade in E. coli RARE.

Chembiochem : a European journal of chemical biology·2026
Same journal

Composite Dissolvable Microneedle-Enabled Local High-Dose Delivery of Endogenous Thiols for Efficient Allergic Dermatitis Treatment.

Chembiochem : a European journal of chemical biology·2026
Same journal

Revisiting the Radical Quenching Activity of Ebselen Analogues in Homogeneous Phase and In Silico Anti-ferroptotic Activity with Histone Deacetylase.

Chembiochem : a European journal of chemical biology·2026
Same journal

Reaction Optimization for Enzymatic Deconstruction of Industrially Relevant Nylon Composites.

Chembiochem : a European journal of chemical biology·2026
Same journal

Deploying Artificial Metalloenzymes in Complex Environments: Strategies and Applications.

Chembiochem : a European journal of chemical biology·2026
Same journal

Synthetic Ligands of Myeloid C-Type Lectin Receptors.

Chembiochem : a European journal of chemical biology·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae
04:51

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae

Published on: July 8, 2025

920

Catalysing mirror life.

Marleen Renders1, Vitor B Pinheiro

  • 1Laboratory for Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000, Leuven (Belgium).

Chembiochem : a European Journal of Chemical Biology
|March 6, 2015
PubMed
Summary
This summary is machine-generated.

The origin of life may not have required homochirality. Researchers isolated cross-chiral nucleic acid ligases, suggesting early life could have been heterochiral.

Keywords:
RNA worlddirected evolutionorigin of liferibozyme

More Related Videos

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy
12:51

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy

Published on: December 9, 2013

9.5K
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.3K

Related Experiment Videos

Last Updated: Apr 16, 2026

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae
04:51

A Modified Mirror Test as a Visual Guide for the Self-awareness Trait in Wild Antarctica Penguins, Pygoscelis adeliae

Published on: July 8, 2025

920
Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy
12:51

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy

Published on: December 9, 2013

9.5K
Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points
09:30

Patterned Photostimulation with Digital Micromirror Devices to Investigate Dendritic Integration Across Branch Points

Published on: March 2, 2011

16.3K

Area of Science:

  • Origin of life studies
  • Biochemistry
  • Molecular evolution

Background:

  • Current life is homochiral, utilizing only D-sugars in nucleic acids.
  • The emergence of homochirality during early life remains poorly understood.
  • It is uncertain if homochirality was a prerequisite for life's origin.

Purpose of the Study:

  • To investigate the possibility of early heterochiral life.
  • To explore alternative pathways for the origin of life.

Main Methods:

  • Isolation and characterization of cross-chiral nucleic acid ligases.
  • Biochemical assays to assess enzyme activity.

Main Results:

  • Successfully isolated nucleic acid ligases capable of acting on both D- and L-nucleic acids (cross-chiral).
  • Demonstrated the enzymatic capability to ligate mixed-chirality nucleic acids.

Conclusions:

  • Early life could have been heterochiral, possessing a mixture of D- and L-nucleic acids.
  • Homochirality may not have been a necessary condition for the origin of life.
  • The discovery provides a new perspective on prebiotic chemistry and the evolution of homochirality.