Office-Based Balloon Sinus Dilation: 1-Year Follow-up of a Prospective, Multicenter Study.

Area of Science:

• Otolaryngology
• Minimally Invasive Surgery
• Rhinosinusitis Research

Background:

• Chronic rhinosinusitis (CRS) significantly impacts patient quality of life.
• Office-based balloon sinus dilation (BSD) presents a minimally invasive treatment option for CRS.
• Evaluating long-term outcomes of office-based BSD is crucial for understanding its efficacy.

Purpose of the Study:

• To assess patient-reported outcomes one year after office-based balloon sinus dilation (BSD) in adults with chronic rhinosinusitis (CRS).
• To determine the durability of quality of life improvements following BSD.
• To evaluate the rate of revision surgery after office-based BSD.

Main Methods:

• Prospective, multicenter, single-arm study involving adult patients with medically refractory CRS.
• Office-based BSD performed under local anesthesia.
• Follow-up assessments at 2, 8, and 24 weeks using SNOT-20 (quality of life) and Lund-Mackay (CT imaging) scores, with a subsequent 1-year follow-up for re-enrolled patients.

Main Results:

• 122 patients completed the 1-year follow-up (average 1.4 years).
• Statistically significant and clinically meaningful improvements in SNOT-20 scores were maintained at 1 year compared to baseline (P < .001).
• Revision surgery was required in 7.4% of patients within the follow-up period.

Conclusions:

• Office-based balloon sinus dilation (BSD) provides sustained improvements in quality of life for patients with chronic rhinosinusitis (CRS) up to one year post-procedure.
• The observed improvements are both statistically significant and clinically meaningful.
• Office-based BSD is an effective and minimally invasive option for carefully selected CRS patients.