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The accessory limb model: an alternative experimental system of limb regeneration
Tetsuya Endo1, David M Gardiner, Aki Makanae
1Division of Liberal Arts and Sciences, Aichi Gakuin University, Nissin, Aichi, 470-0195, Japan.
Methods in Molecular Biology (Clifton, N.J.)
|March 6, 2015
Abstract:
Accessory limb model (ALM) was developed as an experimental model and functional assay for limb regeneration. The ALM provides several ways to identify pathways and test for signaling molecules that regulate limb regeneration. Here, we summarize the history of the ALM and describe the specific details involved in inducing ectopic blastemas and limbs from a skin wound on the side of the arm.

