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Related Concept Videos

Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Essential Minerals for Bone Health01:31

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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
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The Functions of the Skeletal System01:22

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The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
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Alzheimer's Disease: Overview01:26

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Related Experiment Video

Updated: Apr 16, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

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Bone mineral density, adiposity, and cognitive functions.

Hamid R Sohrabi1, Kristyn A Bates2, Michael Weinborn3

  • 1School of Medical Sciences, Edith Cowan University Joondalup, WA, Australia ; The McCusker Alzheimer's Research Foundation Nedlands, WA, Australia ; School of Psychiatry and Clinical Neurosciences, University of Western Australia Crawley, Australia.

Frontiers in Aging Neuroscience
|March 6, 2015
PubMed
Summary
This summary is machine-generated.

Bone mineral density and lean body mass are linked to better episodic memory, a key aspect of cognitive function. This suggests these modifiable factors may play a role in preventing cognitive decline.

Keywords:
agingapolipoprotein Ebone mineral densitycognitiondual energy x-ray absorptiometryepisodic verbal memoryexecutive function

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Alzheimer's disease (AD) and cognitive decline are linked to genetic, lifestyle, and environmental factors.
  • Potentially modifiable risk factors are crucial for interventions targeting dementia.
  • Bone mineral density (BMD) and body composition are identified as such factors.

Purpose of the Study:

  • To investigate the association between BMD, body composition, and cognitive decline.
  • To examine the longitudinal relationship between these factors and cognitive function.

Main Methods:

  • 164 participants (aged 34-87) underwent cognitive and clinical examinations over 3 years.
  • Dual energy x-ray absorptiometry (DXA) measured BMD and body composition.
  • Hierarchical regression analysis assessed predictors of episodic memory, controlling for age, gender, APOE status, and IQ.

Main Results:

  • BMD and lean body mass significantly predicted episodic memory.
  • The List A learning subtest of the California Verbal Learning Test showed significant association with BMD and lean mass at baseline and follow-up.

Conclusions:

  • Significant association exists between BMD, lean body mass, and episodic verbal learning.
  • Further research is needed to elucidate the underlying mechanisms linking these modifiable factors to cognitive function.