Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

46
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
46
Viral Meningitis01:18

Viral Meningitis

156
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
156
Diphtheria01:28

Diphtheria

144
Diphtheria is an acute, toxin-mediated infectious disease that primarily affects the upper respiratory tract. It is caused by Corynebacterium diphtheriae, a Gram-positive, pleomorphic rod that lacks spore-forming capability and exhibits a characteristic club-shaped morphology under microscopic examination. While C. diphtheriae can asymptomatically colonize mucosal surfaces, clinical disease manifests only when the bacterial strain is lysogenized by a specific β-corynephage. This phage...
144
Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

5.0K
The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
5.0K
Influenza01:27

Influenza

57
Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
57

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization and Parallelization of Sorting by Interfacial Tension (SIFT) for High-Throughput Metabolic Cell Sorting.

Micromachines·2026
Same author

Recognising CADASIL in adults with NPH-like syndrome.

BMJ case reports·2026
Same author

Venous sinus stenting worsening in fulminant intracranial hypertension secondary to <i>Cryptococcus gattii</i>: lessons learnt.

BMJ case reports·2026
Same author

Paroxysmal Behavioral Disturbances, Seizures, and Periventricular White Matter Disease Mimicking Leukodystrophy in Niemann-Pick C: A Clinical Vignette.

Pediatric neurology·2026
Same author

Surface anticoagulation of mechanical heart valves using electrically induced biomimetic glycocalyx: An in-vitro study to assess hemocompatibility and optimal voltage.

PloS one·2026
Same author

Fiducial Confidence Intervals for Agreement Measures Among Raters Under a Generalized Linear Mixed Effects Model.

Statistics in medicine·2026
Same journal

Hepatitis B Infection-Associated Aortoarteritis.

Annals of Indian Academy of Neurology·2026
Same journal

Correspondence- Muscle Magnetic Resonance Imaging Phenotyping and Pattern Recognition in Genetically Confirmed Myopathies: A Large-Cohort Study from the Indian Subcontinent.

Annals of Indian Academy of Neurology·2026
Same journal

STAC3-Related Congenital Myopathy (CMYP13) in an Adult Indian Patient: Expanding the Geographic Spectrum to India.

Annals of Indian Academy of Neurology·2026
Same journal

A Prospective Study on Autonomic Functions in Idiopathic Inflammatory Myopathies: The AFIIM Study.

Annals of Indian Academy of Neurology·2026
Same journal

Magnetic Resonance Imaging Findings During Encephalopathic Crisis in Glutaric Aciduria Type 1: Expanding the Radiologic Phenotype.

Annals of Indian Academy of Neurology·2026
Same journal

Thyroid Function and Cognitive Health in Older Adults: Insights from the LASI-DAD Study.

Annals of Indian Academy of Neurology·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

7.3K

"Dot sign" in dengue encephalitis.

Thomas Mathew1, Sagar Badachi1, Gosala Raja Kukkuta Sarma1

  • 1Department of Neurology, St John's Medical College Hospital, Bangalore, Karnataka, India.

Annals of Indian Academy of Neurology
|March 7, 2015
PubMed
Summary
This summary is machine-generated.

Dengue encephalitis typically shows non-specific neuroimaging. This case highlights transient splenial hyperintensity, a "dot sign," on brain MRI in Dengue encephalitis.

Keywords:
Dengue encephalitisdot signtransient splenial hyperintensity

More Related Videos

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum
07:06

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

Published on: April 10, 2018

9.2K
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.1K

Related Experiment Videos

Last Updated: Apr 16, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

7.3K
A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum
07:06

A Simple Flow Cytometry Based Assay to Determine In Vitro Antibody Dependent Enhancement of Dengue Virus Using Zika Virus Convalescent Serum

Published on: April 10, 2018

9.2K
Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
06:18

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

15.1K

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Dengue encephalitis is a serious neurological complication of Dengue virus infection.
  • Neuroimaging findings in Dengue encephalitis are often non-specific, posing diagnostic challenges.

Purpose of the Study:

  • To report a unique neuroimaging finding in a confirmed case of Dengue encephalitis.
  • To describe the transient splenial hyperintensity, or "dot sign," observed on MRI.

Main Methods:

  • A case of Dengue encephalitis was investigated.
  • Magnetic resonance imaging (MRI) of the brain was performed to evaluate neurological findings.

Main Results:

  • The patient presented with Dengue encephalitis.
  • Brain MRI revealed transient splenial hyperintensity, characterized as a "dot sign."

Conclusions:

  • The "dot sign" on brain MRI can be an indicator of Dengue encephalitis.
  • This specific finding, though transient, may aid in the diagnosis of Dengue encephalitis.