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Updated: Apr 16, 2026

Isolation of Murine Intestinal Mesenchyme Resulting in a High Yield of Telocytes
Published on: March 24, 2023
Transmission Electron Microscopy as Key Technique for the Characterization of Telocytes
Irene Cantarero1, Maria Jose Luesma, Jose Miguel Alvarez-Dotu
1Department of Cellular Biology, Physiology and Immunology, Faculty of Medicine, University of Cordoba, Avda. Menéndez Pidal, s/n., 14004 Córdoba, Spain. b12cacai@uco.es.
Abstract:
It was 50 years ago when the details of cellular structure were first observed with an electron microscope (EM). Today, transmission electron microscopy (TEM) still provides the highest resolution detail of cellular ultrastructure. The existence of telocytes (TCs) has been described by Hinescu and Popescu in 2005 and up to now, many studies have been done in different tissues. EM has been fundamental in identification and recognition of TC and relationship between TC and stem cells (SCs) in recent years. We present a review on the importance of TEM to provide major advances in the knowledge of the biology of these cells.
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