Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Muscles of the Eye01:20

Muscles of the Eye

6.2K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
6.2K
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

4.7K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
4.7K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

12.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
12.1K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

7.8K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
7.8K
Actor-Observer Effect01:23

Actor-Observer Effect

553
The actor-observer effect, a cognitive bias closely linked to the fundamental attribution error, refers to the tendency for individuals to attribute their behavior to external, situational factors while explaining others’ behavior in terms of internal, dispositional traits. This asymmetry in attribution significantly influences social perception and judgment.Cognitive Mechanisms Behind the EffectTwo primary psychological mechanisms contribute to the actor-observer effect: differences in...
553

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel <i>cyp26c1</i>-driven reporter line to study boundaries of retinoic acid signalling during zebrafish development.

Frontiers in cell and developmental biology·2026
Same author

Neuropilin 1 (NRP1) conveys SEMA3A signals to restrict physiological angiogenesis.

Angiogenesis·2026
Same author

Recessive loss of DIAPH1 function causes a progressive neurodevelopmental syndrome with variable immunological involvement.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

ZebRack: A budget-friendly mobile system for short-term zebrafish housing.

Cells & development·2026
Same author

A gal4 insertion in the rx3 locus as a tool for visualization and manipulation of eye fated cells in zebrafish.

Biological research·2025
Same author

frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma.

Disease models & mechanisms·2025
Same journal

Temporal trajectories underlying adult neuronal diversity.

Current opinion in genetics & development·2026
Same journal

Transcription regulation of cell fate plasticity - from embryonic development to tissue regeneration.

Current opinion in genetics & development·2026
Same journal

Shared molecular and cellular programs during regeneration of glandular epithelia.

Current opinion in genetics & development·2026
Same journal

Lineage tracing in human cortical development.

Current opinion in genetics & development·2026
Same journal

Cis-regulatory strategies in developmental patterning.

Current opinion in genetics & development·2026
Same journal

GABAergic neuron fate specification and lineage allocation: from development to disorder.

Current opinion in genetics & development·2026
See all related articles

Related Experiment Video

Updated: Apr 16, 2026

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos
06:45

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos

Published on: May 29, 2020

4.7K

Watching eyes take shape.

Naiara Bazin-Lopez1, Leonardo E Valdivia1, Stephen W Wilson1

  • 1Department of Cell and Developmental Biology, UCL, Gower Street, London WC1E 6BT, United Kingdom.

Current Opinion in Genetics & Development
|March 10, 2015
PubMed
Summary
This summary is machine-generated.

Vertebrate eye formation involves complex cell movements and shape changes. This review highlights recent advances in understanding optic vesicle development using zebrafish and stem cell models.

More Related Videos

Eye Tracking During Visually Situated Language Comprehension: Flexibility and Limitations in Uncovering Visual Context Effects
07:36

Eye Tracking During Visually Situated Language Comprehension: Flexibility and Limitations in Uncovering Visual Context Effects

Published on: November 30, 2018

16.6K
Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

11.7K

Related Experiment Videos

Last Updated: Apr 16, 2026

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos
06:45

Loneliness Assuaged: Eye-Tracking an Audience Watching Barrage Videos

Published on: May 29, 2020

4.7K
Eye Tracking During Visually Situated Language Comprehension: Flexibility and Limitations in Uncovering Visual Context Effects
07:36

Eye Tracking During Visually Situated Language Comprehension: Flexibility and Limitations in Uncovering Visual Context Effects

Published on: November 30, 2018

16.6K
Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

11.7K

Area of Science:

  • Developmental biology
  • Cellular morphogenesis
  • Ophthalmology

Background:

  • Vertebrate eye development requires precise inductive interactions between germ layers.
  • Eye morphogenesis involves intricate cellular choreography, including shape changes and tissue movements.
  • The developing eye serves as a model system for studying complex tissue morphogenesis.

Purpose of the Study:

  • To review recent advances in understanding vertebrate eye formation.
  • To highlight key cellular mechanisms driving optic vesicle development.
  • To discuss insights gained from zebrafish and embryonic stem cell studies.

Main Methods:

  • Review of recent scientific literature on eye development.
  • Analysis of cellular and epithelial movements during optic vesicle formation.
  • Integration of findings from in vivo (zebrafish) and in vitro (stem cell) models.

Main Results:

  • Optic vesicle formation is a dynamic process involving coordinated cell behaviors.
  • Specific cellular shape changes and movements are critical for eye morphogenesis.
  • Zebrafish and embryonic stem cell models provide valuable insights into conserved developmental mechanisms.

Conclusions:

  • Understanding the cellular basis of eye development is crucial for regenerative medicine and treating eye diseases.
  • Recent research has significantly advanced our knowledge of the cellular mechanisms shaping the vertebrate eye.
  • The study of optic vesicle formation continues to offer profound insights into fundamental principles of tissue morphogenesis.