Related Experiment Video
Updated: Apr 16, 2026
11:08
Analysis of Cell Suspensions Isolated from Solid Tissues by Spectral Flow Cytometry
Published on: May 5, 2017
13.7K
[Flow cytometry: a fast method to detect foetomaternal haemorrhage].
Pia Jennes Foli-Andersen1, Gitte Holst Hahn, Morten Hanefeld Dziegiel
1Neonatalklinikken, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. piafoli@hotmail.com.
Ugeskrift for Laeger
|March 10, 2015
Summary
Foetomaternal haemorrhage (FMH) occurs when fetal blood enters maternal circulation, potentially causing newborn anemia. Flow cytometry offers a precise method for detecting FMH in maternal blood, aiding diagnosis of unexplained anemia.
Area of Science:
- Obstetrics and Gynecology
- Neonatology
- Immunology
Background:
- Foetomaternal haemorrhage (FMH) is the passage of fetal blood into maternal circulation.
- While often insignificant, large FMH can lead to severe neonatal anemia.
- Accurate detection of FMH is crucial for timely intervention.
Observation:
- Flow cytometry is a highly precise and rapid analytical technique.
- This method can be applied to maternal blood samples.
- Analysis can be performed both antenatally and postnatally.
Findings:
- Flow cytometry enables accurate quantification of fetal red blood cells in maternal blood.
- The study highlights a case of severe FMH.
- This diagnostic approach aids in identifying the cause of unexplained neonatal anemia.
Implications:
- Clinicians should consider flow cytometry for suspected FMH, especially in cases of unexplained neonatal anemia.
- Early detection and management of FMH can prevent serious neonatal complications.
- Flow cytometry provides a valuable tool for obstetric and neonatal care.
