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Updated: Aug 17, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
[The hemodynamic and neurohumoral reactions induced by submaximal dynamic and isometric loading in hypertension
Abstract:
Changes in systemic hemodynamics and plasma catecholamine levels during and 4 min after the end of bicycle and isometric leg exercise were studied in 12 hypertensive patients. Dynamic exercise increased heart rate more and blood pressure less than isometric exercise; plasma norepinephrine (NE) level rose by 109%. Isometric exercise increased NE level only by 18%, but maximal changes (46%) occurred during recovery, probably reflecting a washout of NE from active muscles after the end of isometric contractions. It is concluded that during static exercise more pronounced pressor effect is associated with less activation of the sympathetic nervous system in comparison with dynamic exercise.
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