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Improved fetal survival with small volume plasmapheresis in Rhesus disease
1Department of Obstetrics and Gynecology Medical College, University of Baghdad, Iraq.
Fifty pregnant multiparas with Rhesus isoimmunization were treated by small volume plasmapheresis initiated at the end of their first trimester. Forty mothers were successfully delivered at 31-38 weeks of babies that survived. There were ten fetal losses, six of these were stillborn, and there were three neonatal deaths, and one abortion. This fetal survival rate is acceptable, and plasmapheresis remains an alternative therapy in locations where immunoprophylaxis is not common.
Fifty pregnant multiparas with Rhesus isoimmunization were treated by small volume plasmapheresis initiated at the end of their first trimester. Forty mothers were successfully delivered at 31-38 weeks of babies that survived. There were ten fetal losses, six of these were stillborn, and there were three neonatal deaths, and one abortion. This fetal survival rate is acceptable, and plasmapheresis remains an alternative therapy in locations where immunoprophylaxis is not common.