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Updated: Apr 16, 2026
07:25
Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
3.9K
[Lower limb amputation: indication, preoperative workup and complications]
Revue Medicale Suisse
|March 11, 2015
Summary
Lower limb amputations, primarily due to peripheral artery disease, require careful level selection for optimal healing and function. Below-knee amputations offer better mobility outcomes than above-knee procedures, though complications are common.
Area of Science:
- Vascular surgery
- Orthopedic surgery
- Rehabilitation medicine
Context:
- Peripheral artery disease is the leading cause of lower limb amputations, accounting for 92% of cases.
- Trauma accounts for the remaining 7% of lower limb amputations.
- Amputation level selection is critical for optimizing healing and limb functionality.
Purpose:
- To review the primary causes of lower limb amputations.
- To discuss the impact of amputation level on healing and functional outcomes.
- To highlight the importance of specialized teams in managing post-amputation complications.
Summary:
- Foot-preserving amputations offer the best functional results but often face slow and challenging healing.
- Following a below-knee amputation, 60% of patients regain ambulation.
- Only 20% of patients with an above-knee amputation achieve autonomous ambulation.
Impact:
- Optimizing amputation level selection can significantly improve patient mobility and quality of life.
- Understanding complication rates emphasizes the need for ongoing, specialized care.
- This review underscores the importance of a multidisciplinary approach in lower limb amputation management.
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