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Ras moves to stay in place

Malte Schmick1, Astrid Kraemer1, Philippe I H Bastiaens2

  • 1Department of Systemic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany.

Trends in Cell Biology
|March 12, 2015
PubMed
Summary

Ras GTPases are crucial for cell signaling, but mutations cause problems. A dynamic system maintains Ras at the plasma membrane, ensuring proper signaling function.

Keywords:
PDEδ–Arl2 delivery systemRas localizationRas signalingrecycling endosomespatial cycles

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