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Related Experiment Video

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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Down syndrome: a risk factor for malocclusion severity?

Leandro Silva Marques1, Carlos Eduardo Pinto Alcântara2, Luciano José Pereira3

  • 1Department of Dentistry, School of Biologic and Health Sciences, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, MG, Brazil.

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|March 12, 2015
PubMed
Summary
This summary is machine-generated.

Individuals with Down syndrome (DS) experience significantly more malocclusion and occlusal problems compared to the general population. Factors like premature birth and facial type also contribute to malocclusion severity in DS.

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Area of Science:

  • Dentistry
  • Genetics
  • Public Health

Background:

  • Malocclusion is a common dental issue with various contributing factors.
  • Down syndrome (DS) is associated with distinct craniofacial characteristics that may influence oral health.
  • Understanding malocclusion in individuals with DS is crucial for targeted dental care.

Purpose of the Study:

  • To compare malocclusion aspects between individuals with Down syndrome and a control group.
  • To determine the severity of malocclusion in individuals with DS.
  • To identify factors contributing to malocclusion severity in this population.

Main Methods:

  • A comparative study involving 120 participants (60 with DS, 60 controls).
  • Data collection via interviews, medical chart analysis, and oral examinations.
  • Malocclusion diagnosis using the Dental Aesthetic Index criteria; statistical analysis with Chi-square and logistic regression.

Main Results:

  • Significant differences in missing teeth, diastema, overjet, mandibular protrusion, open bite, crossbite, facial type, lip incompetence, and Angle classification were observed between groups.
  • Down syndrome, premature birth history, and long face pattern were associated with increased malocclusion severity.
  • Individuals with DS demonstrated a higher prevalence of occlusal problems.

Conclusions:

  • Individuals with Down syndrome exhibit a greater burden of malocclusion and occlusal issues compared to controls.
  • Specific clinical and demographic factors are linked to malocclusion severity in individuals with DS.
  • Findings highlight the need for specialized dental monitoring and interventions for individuals with Down syndrome.