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Low-dose CT coronary angiography with a novel IntraCycle motion-correction algorithm in patients with high heart rate

Daniele Andreini1, Gianluca Pontone2, Saima Mushtaq2

  • 1Centro Cardiologico Monzino, IRCCS, Milan, Italy Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Via C. Parea 4, Milan 20138, Italy daniele.andreini@ccfm.it.

European Heart Journal. Cardiovascular Imaging
|March 13, 2015
PubMed

Insights

A new motion-correction (MC) algorithm significantly reduces motion artefacts in coronary CT angiography (CCTA) for patients with high heart rates (HR). This improves image quality and coronary assessability, even at low radiation doses.

Area of Science:

  • Radiology
  • Cardiovascular Imaging
  • Medical Imaging Technology

Background:

  • Motion artefacts are a significant limitation in coronary computed tomography angiography (CCTA), particularly with high or irregular heart rates (HR).
  • These artefacts can compromise image quality and hinder accurate assessment of coronary arteries.

Purpose of the Study:

  • To evaluate the effectiveness of a novel motion-correction (MC) algorithm in reducing motion artefacts during low-dose prospective ECG-triggering CCTA.
  • To assess the impact of the MC algorithm on overall image quality and the assessability of coronary arteries in challenging patient groups.

Main Methods:

  • A study involving 120 patients with high HR (>70 bpm) or heart rate variability (HRv) (>10 bpm) undergoing CCTA.
  • Comparison of image reconstruction using a new MC algorithm versus standard (STD) reconstruction.
  • Analysis of coronary assessability, artefact reduction, image quality, and radiation dose (effective dose measured in mSv).

Main Results:

  • Coronary assessability was significantly higher with MC (97%) compared to STD (81%) (P < 0.0001).
  • MC significantly reduced severe artefacts (54 vs. 356 cases, P < 0.0001) and motion/chest movement artefacts.
  • A higher number of coronary segments achieved excellent image quality with MC (P < 0.001).
  • Mean effective radiation dose was low, particularly with 80 ms padding (2.4 ± 0.9 mSv).

Conclusions:

  • The MC algorithm substantially enhances CCTA image quality and coronary artery visualization in patients with high HR and HRv.
  • This technology offers improved diagnostic accuracy without increasing radiation exposure.
  • The MC algorithm represents a valuable advancement for CCTA in routine clinical practice.
Abstract

Keywords:
Computed tomography coronary angiographyMotion correction algorithmRadiation exposure

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