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Updated: Apr 16, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
Hepatocellular carcinoma rupture following transarterial chemoembolization
Nimarta Singh Bhinder1, Steven M Zangan1
1Department of Radiology, Section of Interventional Radiology, University of Chicago, Chicago, Illinois.
Transarterial chemoembolization (TACE) can rarely cause liver cancer rupture. This case report details successful management of hepatocellular carcinoma (HCC) rupture following TACE using coil embolization.
Area of Science:
- Oncology
- Interventional Radiology
Background:
- Liver cancer incidence is rising globally.
- Transarterial chemoembolization (TACE) is a key minimally invasive treatment for liver cancer.
- While generally safe, TACE carries rare risks, including tumor rupture and hemorrhage.
Purpose of the Study:
- To highlight a rare complication of TACE: hepatocellular carcinoma (HCC) rupture.
- To present a successful management strategy for TACE-induced HCC rupture.
Main Methods:
- Literature review on TACE complications and HCC rupture.
- Case report detailing a patient with HCC rupture post-TACE.
- Interventional radiology procedure using coil embolization for hemorrhage control.
Main Results:
- Hepatocellular carcinoma (HCC) rupture following TACE is a rare but critical complication.
- Successful hemorrhage control and patient management were achieved using coil embolization.
Conclusions:
- Early recognition of HCC rupture post-TACE is crucial.
- Coil embolization represents an effective treatment option for managing TACE-induced HCC rupture.
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