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Laryngeal paraganglioma: a case report
Shervin Sharifkashany1, Nasrin Yazdani2, Hossein Ghazavi2
1Department of Radiology, Amir-Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Summary
This study presents a rare case of a 34-year-old female with multiple paragangliomas, uniquely featuring initial laryngeal involvement. This finding expands understanding of paraganglioma presentation and multicentricity.
Area of Science:
- Neuro-oncology
- Head and Neck Surgery
Background:
- Paragangliomas are typically found in the head and neck, often associated with the carotid body, jugular body, and cranial nerves IX and X.
- Multicentric paragangliomas can occur, but laryngeal paragangliomas are rarely associated with synchronous lesions elsewhere.
Observation:
- A case report of a 34-year-old female patient with multiple paragangliomas is presented.
- The patient's condition uniquely began with laryngeal paraganglioma involvement.
Findings:
- This case represents only the third reported instance of laryngeal paraganglioma occurring with a synchronous lesion in a patient.
- The presentation highlights an unusual initial manifestation of multicentric paraganglioma.
Implications:
- This case underscores the importance of considering multicentric disease even with initial laryngeal paraganglioma presentation.
- Further research into the genetic and clinical factors associated with synchronous paragangliomas, particularly those involving the larynx, is warranted.
