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Updated: Jul 8, 2025

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Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
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Omega-3 Adjunctive Therapy in Idiopathic SSNHL: A Randomised, Triple-Blind, Placebo-Controlled Trial
Benyamin Rahmaty1, Kayvan Aghazadeh1, Sasan Dabiri1
1Otorhinolaryngologist-Head and Neck Surgeon, Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Iranian Journal of Otorhinolaryngology
|December 11, 2023
Summary
Omega-3 fatty acid supplementation did not improve outcomes for idiopathic sudden sensorineural hearing loss (SSNHL). Vertigo and underlying conditions significantly impacted hearing recovery in SSNHL patients.
Area of Science:
- Otolaryngology
- Neurology
- Nutritional Science
Background:
- Idiopathic Sudden Sensorineural Hearing Loss (SSNHL) is defined by rapid hearing decline.
- Vascular events are a suspected cause of SSNHL.
- Omega-3 fatty acids show a potential inverse relationship with hearing loss.
Purpose of the Study:
- To assess the effectiveness of Omega-3 fatty acids as an add-on treatment for SSNHL.
- To evaluate audiometric outcomes in patients receiving Omega-3 therapy.
Main Methods:
- A randomized, triple-blind, placebo-controlled trial was conducted.
- Participants aged 18-70 with recent SSNHL were enrolled.
- Patients were randomized into either an Omega-3 or placebo group.
Main Results:
- No significant difference in hearing improvement was observed between the Omega-3 and placebo groups.
- Complete response occurred in 50% of patients.
- Vertigo and pre-existing conditions were linked to poorer SSNHL recovery.
Conclusions:
- Omega-3 adjunctive therapy showed no therapeutic benefit for SSNHL.
- Vertigo and underlying health issues negatively affect SSNHL recovery.
- Further research may explore other therapeutic avenues for SSNHL.

