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A Randomized Controlled Study to Examine the Effect of a Lifestyle Modification Program in OSA
Susanna S S Ng1, Ruth S M Chan2, Jean Woo2
1Division of Respiratory Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong, China.
Chest
|March 13, 2015
Summary
Weight reduction through a lifestyle modification program (LMP) significantly reduced obstructive sleep apnea (OSA) severity and daytime sleepiness in patients. These positive effects on OSA and well-being were sustained for 12 months.
Area of Science:
- Sleep Medicine
- Obesity Research
- Lifestyle Interventions
Background:
- Obesity is a significant risk factor for Obstructive Sleep Apnea (OSA).
- Understanding the impact of weight management on OSA severity is crucial for patient care.
Purpose of the Study:
- To evaluate the effectiveness of a lifestyle modification program (LMP) in reducing OSA severity.
- To assess the impact of weight reduction on moderate to severe OSA patients.
Main Methods:
- A 12-month parallel-group randomized controlled trial involving 104 patients with moderate to severe OSA.
- Patients were assigned to either a dietician-led LMP or usual care.
- The primary outcome was the change in apnea-hypopnea index (AHI) measured by home sleep monitoring.
Main Results:
- The LMP group showed a significant reduction in AHI compared to the control group (16.9% vs. 0.6% change).
- LMP led to a significant decrease in Body Mass Index (BMI) (-1.8 kg/m2).
- Improvements in daytime sleepiness and mental health were observed in the LMP group.
Conclusions:
- A lifestyle modification program is effective in reducing OSA severity.
- Weight reduction through LMP leads to sustained improvements in OSA and related symptoms.
- LMP positively impacts daytime sleepiness and overall well-being in OSA patients.
