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Active polymer translocation in the three-dimensional domain.

A Fiasconaro1,2,3, J J Mazo1,2, F Falo1,4

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Summary
This summary is machine-generated.

This study investigates polymer translocation through nanochannels under time-dependent forces. Researchers found resonant minima in translocation time and consistent scaling with polymer length across different driving forces.

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Area of Science:

  • Polymer physics
  • Nanotechnology
  • Statistical mechanics

Background:

  • Polymer translocation through nanopores is crucial for DNA sequencing and drug delivery.
  • Understanding the dynamics of polymer movement under external forces is key to controlling these processes.

Purpose of the Study:

  • To investigate the effect of time-dependent forces on polymer translocation dynamics through nanochannels.
  • To compare the outcomes of deterministic sinusoidal driving versus random telegraph noise force.

Main Methods:

  • Simulations of polymer translocation through a nanochannel.
  • Application of time-dependent forces: sinusoidal and telegraph noise.
  • Analysis of mean translocation time, polymer length scaling, and polymer rigidity effects.

Main Results:

  • Observed resonant minima in mean translocation time as a function of driving frequency.
  • Translocation time scales with polymer length via a power law, with a consistent exponent across frequencies for both driving types.
  • Polymer rigidity influences translocation time, showing distinct low-frequency dependencies for the two driving forces.

Conclusions:

  • Time-dependent forces significantly impact polymer translocation dynamics in nanochannels.
  • Resonant phenomena and universal scaling behaviors are identified, offering insights into controlling translocation.
  • The choice of driving force (deterministic vs. stochastic) affects the role of polymer rigidity at low frequencies.