Related Experiment Video
Updated: Apr 16, 2026
09:54
Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
10.8K
HIV diagnosis in a patient presenting with vasculitis
International Journal of STD & AIDS
|March 15, 2015
Summary
A patient with digital ischemia and gangrene improved with HIV treatment. This case highlights that vasculitis can be an early symptom of human immunodeficiency virus (HIV) infection.
Area of Science:
- Vascular Medicine
- Infectious Diseases
- Immunology
Background:
- Vasculitis is a known complication of HIV infection.
- Early diagnosis and treatment of HIV are crucial for managing associated conditions.
- Digital ischemia and gangrene can be manifestations of systemic vasculitis.
Observation:
- A patient presented with digital ischemia and gangrene.
- Initial investigations revealed a positive human immunodeficiency virus (HIV) test.
- Vasculitic screen was otherwise negative, suggesting a link to HIV.
Findings:
- Treatment with antiretroviral medications led to significant improvement in vasculitis symptoms.
- This indicates a strong correlation between HIV infection and the presented vasculitis.
- The patient's vasculitis resolved with targeted HIV therapy.
Implications:
- HIV should be considered in the differential diagnosis of vasculitis, especially in patients with suggestive symptoms.
- Prompt initiation of antiretroviral therapy can effectively manage HIV-associated vasculitis.
- This case underscores the importance of recognizing rare presentations of HIV infection.
More Related Videos
Related Concept Videos
01:22Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
1.2K
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
1.2K
01:27Cytomegalovirus Disease
60
Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
60
01:20Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
445
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
445
01:25Immunodeficiency Diseases
3.6K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
3.6K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
704
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
704
01:27Myocarditis II: Clinical Features and Diagnostic Tests
466
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
466