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[Digestive manifestations during systemic scleroderma].

S Gane, L Boicescu

    Revista De Medicina Interna, Neurologe, Psihiatrie, Neurochirurgie, Dermato-Venerologie. Medicina Interna
    |November 1, 1989
    PubMed
    Summary
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    Systemic scleroderma often affects the digestive tract, with esophageal issues appearing first. Digestive problems in these patients are linked to Raynaud

    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Dermatology

    Context:

    • Systemic scleroderma is a chronic autoimmune disease affecting connective tissues.
    • Digestive manifestations are common in systemic scleroderma, impacting quality of life.
    • Understanding the progression and correlation of these manifestations is crucial for patient management.

    Purpose:

    • To investigate the prevalence and characteristics of digestive manifestations in patients with systemic scleroderma.
    • To determine the pattern of digestive tract involvement and its relationship with disease duration and other symptoms.
    • To assess the impact of digestive involvement on the prognosis of systemic scleroderma.

    Summary:

    • A 3-year study of 32 systemic scleroderma patients found 23 experienced digestive issues affecting the entire gastrointestinal tract.

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  • Esophageal involvement was consistently the first sign, followed by other segments in prolonged disease forms.
  • Digestive manifestations appeared after skin symptoms and were correlated with Raynaud's syndrome, but did not affect overall prognosis.

    • Impact:

    • Provides insights into the natural history and clinical presentation of gastrointestinal complications in systemic scleroderma.
    • Highlights the importance of recognizing and managing digestive symptoms in this patient population.
    • Suggests that while common, digestive involvement may not alter the fundamental prognosis of systemic scleroderma.