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Published on: November 28, 2025
Transitional care in solid organ transplantation
Nanda Kerkar1, Rachel Annunziato2
1Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Los Angeles, University of Southern California, 4650 Sunset Blvd, #147, Los Angeles, California 90027.
Insights
Pediatric solid organ transplant recipients are increasingly surviving to adulthood. Successful transition to adult care programs requires careful planning and coordination to improve long-term outcomes and quality of life.
Area of Science:
- Pediatric and adult solid organ transplantation
- Transplant recipient care coordination
- Healthcare transition services
Background:
- Pediatric solid organ transplantation is increasingly successful, leading to more survivors reaching adulthood.
- The transition from pediatric to adult healthcare services presents unique challenges for these young patients.
- Existing care models may not adequately address the specific needs of adolescent and young adult transplant recipients.
Purpose of the Study:
- To review the epidemiology of pediatric solid organ transplant recipients.
- To identify challenges faced during the transition to adult transplant services.
- To suggest improvements for collaborative and coordinated care during this critical phase.
Main Methods:
- Literature review of pediatric solid organ transplantation and transition care.
- Analysis of epidemiological data for pediatric transplant recipients.
- Synthesis of best practices for healthcare transition programs.
Main Results:
- Transition to adulthood is a vulnerable period for solid organ transplant recipients.
- Key facilitators for successful transition include readiness assessment, adequate preparation time, stakeholder involvement, and transition coordinators.
- Programmatic approaches enhance quality of life and long-term graft and patient survival.
Conclusions:
- A robust transition program improves outcomes for pediatric solid organ transplant survivors.
- Successful transition requires a multidisciplinary, coordinated approach.
- The long-term benefits, including improved survival and reduced healthcare costs, justify investment in transition programs.
Abstract:
Pediatric solid organ transplantation has become an accepted modality of treatment in the last few decades. The number of childhood recipients of solid organ transplantation surviving to adulthood is correspondingly rising. This review examines the epidemiology of pediatric solid organ transplant recipients, and the challenges faced during transition to adult services, with suggestions for improvement in collaborative and coordinated care. Transition to adulthood has been established as a vulnerable period for recipients of a solid organ transplant. Assessment of readiness for transfer, allowing sufficient time for preparation before the actual transfer, involvement of all stakeholders, and inclusion of a transition coordinator are some of the components that can facilitate successful transition to the adult transplant program. This programmatic approach improves both quality of life and long-term graft and patient survival. Moreover, the economic benefits associated with avoiding frequent hospitalizations for graft dysfunction and preventing re-transplantation more than compensate for the costs related to establishing and maintaining a robust transition program.
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