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Composite lymphoma in a patient with ulcerative colitis: a case report
Farzaneh Ashrafi1, Farid Kowsari2, Ali Darakhshandeh3
1Hematology &Oncology section, Department of Internal Medicine, School of Medicine, Isfahan University of Medical sciences, Isfahan, Iran.
Abstract:
A 45-year-old female patient with a diagnosis of ulcerative colitis complicated with composite lymphoma in the spleen and para-aortic lymph node presented with a one-month history of malaise, weakness and fatigue. Only mesalamine kept ulcerative colitis under control. In physical examination, splenomegaly was revealed and pancytopenia was obtained from laboratory data. Computed tomography scan revealed para-aortic mediastinal lymphadenopathy with splenomegaly. Splenectomy and excisional biopsy of abdominal lymph node were performed and disease was diagnosed as composite lymphoma, consisting of diffuse large B-cell lymphoma and nodular sclerosing Hodgkin lymphoma.
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