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Updated: Apr 16, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Pleura space anatomy
Charalampos Charalampidis1, Andrianna Youroukou1, George Lazaridis1
11 Department of Anatomy, Medical School, Democritus University of Thrace, Alexandroupolis, Greece ; 2 Cardiothoracic Surgery Department, "Evangelismos" Hospital, Athens, Greece ; 3 Department of Medical Oncology, Aristotle University School of Medicine, Thessaloniki, Greece ; 4 Oncology Department, "Interbalkan" European Medical Center, Thessaloniki, Greece ; 5 Oncology Department, "BioMedicine" Private Clinic, Thessaloniki, Greece ; 6 Pulmonary-Oncology, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 7 Thoracic Surgery Department, "Saint Luke" Private Hospital, Thessaloniki, Greece ; 8 Surgery Department, University General Hospital of Alexandroupolis, Alexandroupolis, Greece ; 9 Pathology Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 10 Oncology Department, "Saint Luke" Private Hospital, Thessaloniki, Greece.
The pleural cavity is the space between the visceral and parietal pleurae surrounding the lungs. This review details the anatomy of the pleural space, including its layers and innervation.
Area of Science:
- Anatomy
- Pulmonology
- Thoracic Surgery
Background:
- The pleural cavity is a potential space between the visceral and parietal pleurae.
- It normally contains a small amount of pleural fluid.
- The pleurae are serous membranes forming a two-layered structure.
Purpose of the Study:
- To present the anatomy of the pleural space.
- To describe the layers of the pleurae and their relationship to the lungs and chest wall.
- To differentiate the sensory innervation of the parietal and visceral pleurae.
Main Methods:
- Review of anatomical literature.
- Description of pleural layers and their attachments.
- Explanation of pleural fluid dynamics and innervation.
Main Results:
- The pleural cavity is defined by the visceral pleura (lung surface) and parietal pleura (chest wall lining).
- The parietal pleura is pain-sensitive due to rich sensory innervation.
- The visceral pleura lacks sensory nerves and is not sensitive to pain.
Conclusions:
- Understanding pleural anatomy is crucial for diagnosing and treating thoracic conditions.
- The differential innervation explains pain localization in pleural diseases.
- This review provides a foundational anatomical overview of the pleural space.
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