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[Type 1 fimbriae and P fimbriae in E. coli producing chronic prostatitis]
Abstract:
The fimbriated adhesines constitute a factor of virulence of E. coli in the urinary tract infections. The presence of type 1 fimbriae and fimbriae P was evaluated in 23 E. coli strains isolated with patients with chronic bacterial prostatitis. For the diagnosis of prostatitis the Stamey test was used. The detection of the type 1 fimbriae was carried out by agglutination of the E. coli strains with Saccharomyces cerevisiae and that of fimbriae P with PPA test. 95.7% of the evaluated strains had type 1 fimbriae and 52.2% had fimbriae P. It is concluded that type 1 fimbriae are common in all strains associated with urinary tract infection, without any relationship between their presence and the localization of infection, and that the presence of fimbriae P is not a constant feature of the E. coli strains associated with chronic prostatitis.
Insights
Type 1 fimbriae are common in E. coli causing urinary tract infections. However, P fimbriae are not consistently found in E. coli strains linked to chronic bacterial prostatitis.
Area of Science:
- Microbiology
- Urology
- Infectious Diseases
Background:
- Fimbriated adhesins are key virulence factors for E. coli in urinary tract infections (UTIs).
- Chronic bacterial prostatitis involves E. coli infections, where adherence factors may play a role.
Purpose of the Study:
- To investigate the prevalence of type 1 fimbriae and P fimbriae in E. coli strains from patients with chronic bacterial prostatitis.
- To determine the association between these fimbriae and the specific infection site.
Main Methods:
- E. coli strains were isolated from 23 patients diagnosed with chronic bacterial prostatitis using the Stamey test.
- Type 1 fimbriae detection was performed via agglutination with Saccharomyces cerevisiae.
- P fimbriae detection utilized the PPA test.
Main Results:
- Type 1 fimbriae were detected in 95.7% of the E. coli strains evaluated.
- P fimbriae were present in 52.2% of the E. coli strains.
- Type 1 fimbriae were universally present in UTI-associated E. coli, irrespective of infection localization.
Conclusions:
- Type 1 fimbriae are a common characteristic of E. coli strains implicated in UTIs.
- The presence of type 1 fimbriae does not correlate with the specific site of infection.
- P fimbriae are not a constant feature in E. coli strains causing chronic bacterial prostatitis.