Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Biofuels

Biofuels

The microbial conversion of organic matter into biofuels holds potential as a renewable energy source. Among biofuel sources, microalgae are recognized as a highly efficient and adaptable feedstock for biodiesel production, owing to their rapid biomass accumulation, elevated lipid productivity, and capacity to proliferate in diverse aquatic systems, including freshwater, marine, and wastewater habitats. Unlike terrestrial crops, microalgae do not compete for land and can achieve significantly...

Bioremediation

Bioremediation

Bioremediation is the use of prokaryotes, fungi, or plants to remove pollutants from the environment. This process has been used to remove harmful toxins in groundwater as a byproduct of agricultural run-off and also to clean up oil spills.

Bioequivalence: Overview

Bioequivalence: Overview

Pharmaceutical equivalents, by definition, are drug products with the same active ingredient in the same quantities, encapsulated in identical dosage forms, and intended for the same administration routes. These pharmaceutical equivalents are deemed bioequivalent if the bioavailability of the active entity in the drug preparations is similar. Moreover, pharmaceutical equivalents demonstrating bioequivalence are also regarded as therapeutically equivalent. This means that when used as directed,...

Synthetic Biology

Synthetic Biology

Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...

Production of Biopesticides

Production of Biopesticides

Biopesticides offer a sustainable alternative to chemical pesticides, utilizing microbial agents to control agricultural pests. Bacillus thuringiensis (Bt) is a widely employed bacterium known for its potent insecticidal activity. Bt biopesticides are favored for their specificity to insect pests, minimal environmental impact, and natural degradability.Mechanism of Bt Toxin Action Bt produces insecticidal crystal (Cry) proteins during its sporulation phase. These proteins form parasporal...

Ecological Niches

Ecological Niches

All organisms have a position within an ecosystem. The complete set of living and nonliving factors—including food resources, climate, and terrain—that define the position of a given organism are collectively referred to as the organism’s ecological niche.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A novel method to select Reference Proteomes in UniProt.

bioRxiv : the preprint server for biology·2026

Same author

Advances in Protein Function Prediction from the Fifth CAFA Challenge.

bioRxiv : the preprint server for biology·2026

Same author

Expanding the human proteome with microproteins and peptideins.

Nature·2026

Same author

The Potential of Digital Twins for Pediatric Rare Diseases.

CPT: pharmacometrics & systems pharmacology·2026

Same author

From FAIR to CURE: guidelines for computational models of biological systems.

NPJ systems biology and applications·2026

Same author

An expanded reference catalog of translated open reading frames for biomedical research.

Nucleic acids research·2026

Same journal

Development of CypriSSR: a genome-wide, chromosome-level microsatellite database for multiple cyprinidae species.

Database : the journal of biological databases and curation·2026

Same journal

KitBase Expanded: An Integrated Genomic and Phenotypic Resource for 3,268 Fast-Neutron-Irradiated Rice Mutants.

Database : the journal of biological databases and curation·2026

Same journal

PhaLP 2.0: extending the community-oriented phage lysin database with a SUBLYME pipeline for metagenomic discovery.

Database : the journal of biological databases and curation·2026

Same journal

A similarity metric, rubric, and unified hierarchy for biomedical publication types and study designs.

Database : the journal of biological databases and curation·2026

Same journal

GUTAID: a curated database linking gut microbial antigens to autoimmune mechanisms.

Database : the journal of biological databases and curation·2026

Same journal

Rosetta Statements: simplifying FAIR knowledge graph construction with a user-centred approach.

Database : the journal of biological databases and curation·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 16, 2026

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

Shared resources, shared costs--leveraging biocuration resources.

Sandra Orchard¹, Henning Hermjakob²

¹European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK orchard@ebi.ac.uk.

Database : the Journal of Biological Databases and Curation

|March 18, 2015

Summary

This summary is machine-generated.

Manual curation of biomedical data is valuable despite costs. Sharing infrastructure and development efforts among databases offers significant cost savings and ensures data persistence.

More Related Videos

Creation and Maintenance of a Living Biobank - How We Do It

Creation and Maintenance of a Living Biobank - How We Do It

Published on: April 10, 2021

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Related Experiment Videos

Last Updated: Apr 16, 2026

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

Creation and Maintenance of a Living Biobank - How We Do It

Creation and Maintenance of a Living Biobank - How We Do It

Published on: April 10, 2021

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Area of Science:

Biomedical Informatics
Data Curation
Bioinformatics Resource Management

Background:

Manual curation of biomedical data is essential but costly.
Automated annotation and text-mining present less expensive alternatives.
Efficient data management is crucial for scientific advancement.

Purpose of the Study:

To argue for the value of manual curation in biomedical resources.
To explore cost-saving strategies for databases through shared development.
To review successful models of shared curation efforts.

Main Methods:

Comparative analysis of manual curation versus automated methods.
Discussion of infrastructure and tool development sharing.
Case studies of the Gene Ontology (GO) annotation and IntAct molecular interaction database.

Main Results:

Manual curation provides high-quality, reliable data essential for research.
Shared infrastructure and development reduce costs and prevent redundant efforts.
Collaborative models ensure long-term data persistence and accessibility.

Conclusions:

Manual curation remains a vital approach for high-quality biomedical data.
Database collaboration through shared resources is a cost-effective and sustainable model.
Adoption of shared curation efforts enhances data integrity and accessibility for the scientific community.