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Published on: December 6, 2016
Microalbuminuria in obstructive sleep apnea syndrome
Emel Bulcun1, Mehmet Ekici2, Aydanur Ekici2
1Department of Pulmonary Medicine, Faculty of Medicine, University of Kirikkale, 71100, Kirikkale, Turkey. emelbulcun@hotmail.com.
Microalbuminuria is linked to obstructive sleep apnea syndrome (OSAS) severity and hypoxemia. Regular screening for microalbuminuria in OSAS patients is crucial for cardiovascular risk management.
Area of Science:
- Cardiology
- Pulmonology
- Nephrology
Background:
- Microalbuminuria is a key cardiovascular disease risk factor.
- Obstructive Sleep Apnea Syndrome (OSAS) is associated with intermittent hypoxemia.
- The link between OSAS and microalbuminuria requires further investigation.
Purpose of the Study:
- To determine the prevalence of microalbuminuria in OSAS patients.
- To explore the relationship between microalbuminuria and clinical/physiological parameters in OSAS.
- To assess the association between OSAS severity and microalbuminuria.
Main Methods:
- 98 OSAS patients and 26 controls underwent polysomnography.
- Urinary albumin-to-creatinine ratio (UACR) was measured.
- Disease severity (MCIRS), insulin resistance (HOMA-IR), and sleepiness (ESS) were assessed.
Main Results:
- OSAS patients had higher BMI, MCIRS, and UACR than controls.
- UACR showed a negative correlation with minimal O2 levels.
- UACR positively correlated with the desaturation index.
Conclusions:
- Microalbuminuria is prevalent in OSAS patients.
- Disease severity and hypoxemia influence microalbuminuria in OSAS.
- Regular microalbuminuria screening is recommended for OSAS patients to mitigate cardiovascular risks.
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