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Eccrine chromhidrosis secondary to hyperbilirubinemia
1UC San Diego.
Dermatology Online Journal
|March 18, 2015
Summary
Eccrine chromhidrosis, a rare condition of colored sweat, can occur with hyperbilirubinemia. Diagnosis relies on clinical signs, dermoscopy, and negative cultures, distinguishing it from infections.
Area of Science:
- Dermatology
- Gastroenterology
Background:
- Eccrine chromhidrosis, or colored sweat, is typically caused by external factors like dyes or microorganisms.
- Less commonly, it can be linked to internal conditions such as hyperbilirubinemia, affecting areas rich in sweat glands like palms and soles.
Observation:
- This report details a unique case of eccrine chromhidrosis associated with hyperbilirubinemia.
- A review of PubMed identified six prior cases of chromhidrosis in patients with significant hyperbilirubinemia, fever, and thickened stratum corneum.
Findings:
- Eccrine chromhidrosis secondary to hyperbilirubinemia is an exceptionally rare condition.
- Diagnosis is established through characteristic clinical presentation, dermoscopic evaluation, and exclusion of microbial causes via negative tissue cultures.
Implications:
- This case highlights a rare but diagnosable cause of colored sweating.
- Understanding this association aids in accurate diagnosis and management of patients presenting with unusual skin manifestations and elevated bilirubin levels.
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