Treatment of esophageal achalasia in children: Today and tomorrow

Tamara Caldaro1, Pietro Familiari2, Erminia Francesca Romeo1

  • 1Digestive Surgery and Endoscopy Unit, Bambino Gesù Children's Hospital, Rome, Italy.

Insights

Peroral endoscopic myotomy (POEM) and Laparoscopic Heller myotomy (LHM) are safe and effective for treating pediatric esophageal achalasia. POEM offers a shorter operation time compared to LHM.

Area of Science:

  • Pediatric surgery
  • Gastroenterology
  • Minimally invasive procedures

Background:

  • Esophageal achalasia (EA) is a rare pediatric motility disorder.
  • Laparoscopic Heller myotomy (LHM) is the standard treatment.
  • Peroral endoscopic myotomy (POEM) is an emerging alternative.

Purpose of the Study:

  • To evaluate the effectiveness and safety of POEM versus LHM in children with EA.
  • To compare clinical and manometric outcomes between the two procedures.

Main Methods:

  • Retrospective data collection from two centers (Feb 2009 - Dec 2013).
  • Included 18 pediatric patients with EA (9 LHM, 9 POEM).
  • Compared operation time, myotomy length, complications, and follow-up outcomes.

Main Results:

  • POEM had a shorter mean operation time (62 min) than LHM (149 min).
  • POEM involved a longer myotomy (11 cm) than LHM (7 cm).
  • One major complication (esophageal perforation) occurred after LHM; no significant clinical/manometric differences or increased GERD were observed between groups at midterm follow-up.

Conclusions:

  • Both LHM and POEM are safe and effective for pediatric EA.
  • POEM is a minimally invasive option with faster execution.
  • Expertise of the endoscopic team is crucial for successful POEM procedures.
Abstract

Related Concept Videos

Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
362
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
697
Gastroesophageal Reflux Disease II: Clinical Features and Management01:29

Gastroesophageal Reflux Disease II: Clinical Features and Management

Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
626
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
542
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
329
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
1.0K