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SHORT-TERM POSTOPERATIVE COMPLICATIONS AFTER ANORECTAL MALFORMATION RECONSTRUCTION: A 25-YEAR EXPERIENCE
Minoes Borghei1, Cunera M C de Beaufort1, Marijke E B Kremer2
1Emma Children's Hospital Amsterdam UMC, location University of Amsterdam, Department of Pediatric Surgery, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands; Amsterdam Gastroenterology and Metabolism Research Institute, Amsterdam, the Netherlands; Amsterdam Reproduction and Development Research Institute, Amsterdam, the Netherlands.
Aim:
To assess the prevalence and severity of short-term postoperative complications (≤30 days) following anorectal malformation (ARM) reconstruction, and explore potential risk factors for minor and major complications.
Methods:
This retrospective cohort study included all ARM patients born between January 2000 and December 2025 who underwent definitive reconstruction. Short-term postoperative complications were classified according to the Clavien-Madadi classification. Univariable and multivariable logistic regression analyses were performed.
Results:
278 patients were included, of whom 49.6% were female. Median age (IQR) at reconstruction was 4 months (3-6). Short-term postoperative complications occurred in 78 patients (28.1%), including 53 (19.1%) minor and 25 (9.0%) major complications. Wound dehiscence occurred most frequently (n=57; 20.5%). In multivariable analysis, surgical techniques other than ASARP or PSARP were associated with lower odds of minor complications (OR 0.14, 95% CI 0.03-0.62). Major complications were associated with VACTERL association (OR 6.27, 95% CI 2.43-16.22) and inversely with pre-reconstructive colostomy creation (OR 0.26, 95% CI 0.08-0.82).
Conclusions:
Of all patients, 28.1% experienced short-term postoperative complications after ARM reconstruction. Minor complications were associated with type of surgery, whereas major complications were associated with VACTERL association and inversely with pre-reconstructive colostomy creation.
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